Trident Technical College is governed by a nine-member area commission comprised of three members each from Berkeley, Charleston and Dorchester counties. Commission members are appointed by the governor upon the recommendation of the legislative delegations in Berkeley and Charleston counties and by the county council in Dorchester County.

Yvonne D. J. Barnes, Ed.D., Ph.D Berkeley County	William Blanton Berkeley County	Franklin J. Medio, Ph.D. Berkeley County
Wilbur E. Johnson Charleston County	Baird A. Mallory Charleston County	Anita Zucker Charleston County
Jack Y. Harrison Dorchester County	Rutherford P.C. Smith Dorchester County	Marion C. Thompson Dorchester County